5-Fluorouracil and Triamcinolone Treatment for Keloid Scars

At The London Keloid Scar Clinic, we are dedicated to providing cutting-edge treatments to manage and reduce keloid scars effectively. Our combination therapy of 5-Fluorouracil (5-FU) and Triamcinolone offers a powerful solution that targets the underlying causes of keloids while improving their appearance and symptoms. This innovative approach delivers superior results by addressing excessive collagen production and inflammation simultaneously.

Keloid Removal From £150

Before and after results of chest keloid therapy at the clinic.

The London Keloid Scar Clinic 4 Harley Street, London W1G 9PB, United Kingdom

The London Keloid Scar Clinic place picture
4.8
Based on 50 reviews
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Abu Bakarr Sidique profile pictureAbu Bakarr Sidique
14:20 11 Sep 25
Dr. Johnson is one of the best in London for skincare and keloid treatment. Her expertise and care made my experience outstanding, and the results exceeded my expectations.”
Andrew Wilson profile pictureAndrew Wilson
12:52 11 Sep 25
Very positive experience with caring staff. Highly recommend!
Priscilla Kay profile picturePriscilla Kay
14:09 08 Sep 25
Amazing results at this clinic and even better service, especially from Jin. Very lovely staff, you’re treated with so much care and compassion here and the treatments work!
Martha Casbolt profile pictureMartha Casbolt
14:31 04 Sep 25
Efficient and friendly service. Very knowledgable and helpful staff
Evie Gillespie profile pictureEvie Gillespie
11:35 02 Sep 25
Amazing staff! They make you feel very comfortable and they are so professional and friendly. The treatment is great and just what I was looking for!
pirasana jeyanayagan profile picturepirasana jeyanayagan
15:18 22 Aug 25
Mochi_2000 xD profile pictureMochi_2000 xD
10:24 12 Aug 25
I just had my review for my keloid surgery and injections. Had my surgery done like a year ago. My last injection was 7 months ago. Everything went well. The staff are extremely nice and friendly. Definitely recommend coming to this clinic. If I ever feel like getting anything aesthetically done. I’m definitely coming back here.
Akintayo Makinwa profile pictureAkintayo Makinwa
12:32 25 Jul 25
The best treatment so far received . I've done the treatment twice here in London not until i find out about London Keloid Scar Clinic.
You guys are fantastic 👏.
Folake.
Val Palmer profile pictureVal Palmer
16:49 21 Jul 25
Superb service with very kind, friendly staff.
Sibelly Morais profile pictureSibelly Morais
10:15 18 Jul 25
Cristian profile pictureCristian
06:07 09 Dec 24
After visiting this clinic, my scars are barely noticeable. Dr. Johnson’s approach is both effective and compassionate.
Herlinder Gomez profile pictureHerlinder Gomez
05:44 09 Dec 24
I had a wonderful experience at Dr. Johnson's clinic! The staff was friendly and welcoming, making me feel at ease from the start. Dr. Johnson is incredibly knowledgeable and took the time to explain everything to me. The treatment for my keloids has shown remarkable results, and I couldn’t be happier. I highly recommend this clinic to anyone looking for effective scar treatments!
This clinic is well-equipped and the staff is professional. Dr. Johnson’s experience is evident in the care she provides.
Angely Moreno profile pictureAngely Moreno
05:22 09 Dec 24
My experience at Dr. Johnson's clinic was fantastic! The atmosphere is warm and inviting, which made me feel comfortable right away. Dr. Johnson is not only highly skilled but also genuinely caring. She took the time to answer all my questions and provided me with valuable advice. The results of my treatment have been amazing! I highly recommend this clinic for anyone seeking help with keloids
Mariangel Salazar profile pictureMariangel Salazar
05:21 09 Dec 24
The results I’ve seen from my keloid treatment have exceeded my expectations. I can’t recommend this clinic enough!
Haidar Haibatan profile pictureHaidar Haibatan
15:33 21 Nov 24
Yes in regards to Dr Salinda Johnson caring for others is truly inspiring.Your unwavering dedication to your patient health and wellbeing is a beacon of hope and comfort.

The Clinic manager Raheena a truly wonderful person and her staff Victoria.
Kind regards,
Security
H.👍
James B profile pictureJames B
22:14 11 Nov 24
Very impressed with the service at this leading Harley Street clinic. Dr Johnson clearly explained the options and was generous with her time. Good communication and follow up, and the staff were very friendly and helpful. I think the keloid scar treatment offered by this clinic is world leading in that the approach Dr Johnson uses is both unique and delivers results such that there is no grow back.
Salinda Johnson profile pictureSalinda Johnson
14:58 31 Oct 23
This the exceptional second clinic after the great success at the flagship clinic in the world renown Harley street. This clinic is unlike any clinic on high street. It’s an exclusive & rich in interior design providing calming and luxurious atmosphere. The interior and desirable location , off Cadogan square and Lennox garden which is convenient l short walk from Sloane Square & Knightsbridge tube station and HARODS in Knightsbridge & Chelsea giving the highly private VIP and 7 stars experience with the UK top Aestheic doctors and Dermatologists and services from the kind & caring staffs. If you’re looking for a great results, private VIP experience and kind & caring staffs and UK top specialist for non-surgical cosmetic procedures and dermatological concerns, you will find them here. ⭐️⭐️⭐️⭐️⭐️⭐️⭐️
An exclusive and welcoming cosmetic skin clinic with 7 stars service and care by a group of UK leading Aesthetic Dermatologists. This is our new clinic after the success at our flagship clinic in Harley street, London. We look forward to seeing you here.
Yuri Sato profile pictureYuri Sato
16:22 02 Jun 23
I usually go to see Dr. Johnson at Harley Street clinic and am very happy with the doctor, staff and the treatments there but this Chelsea branch gives me more homey and cozy feeling and I love visiting here. All staff are kind and friendly, never forget to offer me a fresh coffee or tea when I wait. I specially like an iv drip treatment as it gives me immediate energy when I'm tired or feel weak.

Keloid Before and After

Keloid on head before and after
Keloid on ear before and after
Forehead keloid before and after treatment with clear reduction.
Beard area keloid before and after images showing treatment success.
Transformation of neck keloid after professional treatment.

Keloid Removal Pricing

Why Choose 5-FU and Triamcinolone for Keloid Treatment?

Keloids can be challenging to treat due to their high recurrence rates and resistance to conventional therapies like surgery or standalone steroid injections. Our combination therapy addresses these challenges with a dual-action approach.

How It Works:

  1. 5-Fluorouracil (5-FU):

    • A low-dose chemotherapy agent that inhibits fibroblasts responsible for excessive collagen production.
    • Reduces scar size and prevents further thickening.
  2. Triamcinolone Acetonide:

    • A corticosteroid that suppresses inflammation and immune responses.
    • Flattens and softens the keloid tissue while relieving symptoms like itching or pain.

Benefits of Combination Therapy:

  • Enhanced efficacy compared to single-agent treatments.
  • Lower recurrence rates than traditional methods.
  • Safe and targeted treatment with minimal side effects.
  • Suitable for keloids of all sizes, locations, and stages.

Our Treatment Process

  • Comprehensive evaluation of your keloid’s characteristics.
  • Review of your medical history and any prior treatments.
  • Development of a tailored treatment plan based on your specific needs.
  • Preparation: The area is cleansed, and a topical anaesthetic may be applied for comfort.
  • Injection: A customised mixture of 5-FU and Triamcinolone is administered directly into the keloid using fine needles.
  • Technique: Multiple small injections ensure uniform medication delivery.
  • Duration: Each session takes approximately 15–30 minutes.
  • Frequency: Injections are administered every 2–4 weeks.
  • Sessions Required: Most patients achieve significant results after 3–6 sessions.
  • Immediate Recovery: Minimal downtime; you can resume daily activities immediately.
  • Side Effects: Mild redness or swelling may occur but typically resolves within 24–48 hours.
  • Aftercare Instructions: Guidance will be provided to optimise healing and results.
  • Visible Improvements:

    • Flattened and softened keloid tissue.
    • Reduced size and height of the scar.
    • Fading of redness or pigmentation.
    • Relief from itching and discomfort.

    Timeline:

    • Initial Results: Improvements are often noticeable after the second or third session.
    • Long-Term Outcome: Gradual enhancements with sustained results when paired with proper aftercare.

At The London Keloid Clinic, we provide a comprehensive consultation and treatment approach. Our doctors carefully examine each case, considering factors such as keloid size, location, and patient preferences to recommend the most suitable treatment. With years of expertise and cutting-edge technology, we have achieved life-changing results for thousands of patients.

Keloid clinic

GET IN TOUCH

If you have any concerns about keloids or would like to discuss treatment options, please get in touch with us. Our friendly team is here to answer your questions and guide you through the next steps.

Why Choose The London Keloid Scar Clinic?

  • Specialised Expertise: Our clinic focuses exclusively on keloid and hypertrophic scar management.
  • Innovative Techniques: We utilise advanced, evidence-based treatments tailored to individual needs.
  • Patient-Centred Care: From consultation to aftercare, we prioritise your comfort and satisfaction.

Have Questions About Keloid Treatment?

We’re here to help. Whether you want to learn more about your condition, explore treatment options, or book a consultation, feel free to contact us. Our experienced team is dedicated to providing the support and care you need.

Frequently Asked Questions

Yes, this combination therapy is effective for older keloids, although they may require more sessions compared to newer scars. The synergistic effect of 5-FU and Triamcinolone can still significantly reduce the size, thickness, and symptoms of long-standing keloids.

The addition of 5-FU inhibits the overproduction of collagen, which is a primary cause of keloid recurrence. When combined with Triamcinolone to reduce inflammation, this therapy lowers the chance of regrowth compared to steroid injections alone.

Yes, the dosage and injection technique are carefully tailored for delicate areas such as the face or neck. Our specialists ensure precise administration to minimise discomfort and maximise safety.

Steroids primarily reduce inflammation and flatten keloids, but they don’t address the cellular overgrowth caused by fibroblasts. 5-FU directly targets these cells, providing a more comprehensive approach to keloid treatment.

Aftercare is crucial to optimise results. Avoid excessive sun exposure and apply any recommended ointments or silicone sheets. Refrain from touching or irritating the treated area for at least 24 hours post-treatment.

While steroids alone may cause skin thinning or discolouration in some cases, the addition of 5-FU reduces the amount of steroid needed, thereby lowering these risks. Any changes are typically temporary and resolve over time.

Yes, this therapy is highly effective as a post-surgical preventive measure to reduce the likelihood of keloid recurrence. It can also be used for residual or regrown keloid tissue.

Treatment can start as soon as the wound has fully healed, typically within 3–4 weeks. Early intervention often leads to better outcomes by targeting scar formation before it matures.

The number of sessions depends on the size, location, and age of the keloid, as well as how it responds to initial treatments. Most patients require 3–6 sessions spaced 2–4 weeks apart.

Absolutely. Multiple keloids can be treated during the same session, with the dosage adjusted for each scar. A tailored plan ensures comprehensive care for all affected areas.

Yes, the anti-inflammatory properties of Triamcinolone provide immediate relief from itching and discomfort, while 5-FU reduces the underlying causes of these symptoms.

Keloid Removal Head Doctor

Dr Salinda Johnson Keloid Docotor
Medical Doctor
Dr. Salinda Johnson, MD., FSCD.

Medical Director & Aesthetic Dermatologist

Dr. Salinda Johnson is a renowned specialist in aesthetic dermatology and one of the UK’s leading experts in keloid scar treatment. With over 20 years of experience, she has performed over 5,000 keloid procedures, including more than 2,000 ear keloid removals. A published author and trainer in aesthetic medicine, Dr. Johnson is dedicated to achieving optimal results using advanced, evidence-based techniques.

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Welcome to our London keloid scar clinic